bsm-30012M-APC

DATASHEET

Host: Mouse

Target Protein: Neprilysin

Clonality: Monoclonal

Isotype: IgG2b/Kappa

Entrez Gene: 4311

Swiss Prot: P08473

Purification: Affinity purified by Protein G

Storage Buffer: 0.01M PBS, 0.5%BSA, 0.02% Proclin300

Storage: Store at 2-8℃. Protect from light. Avoid freezing.

Background:

The protein encoded by this gene is a type II transmembrane glycoprotein and a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). The encoded protein is present on leukemic cells of pre-B phenotype, which represent 85% of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin. [provided by RefSeq, Aug 2017]

Size: 25T,100T

Concentration: n/a

Applications: FCM(10l per million cells in 100l staining volume)

Predicted Molecular Weight: 82

Cross Reactive Species: Human

For research use only. Not intended for diagnostic or therapeutic use.